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It is release in the penis during sexual stimulation and activates an enzyme called guanylate cyclase. This enzyme increases cyclic guanosine monophosphate (cGMP), which then allows blood to flow to the penis. However, a protein called phosphodiesterase type five (PDE5) inhibits the production of cGMP, preventing it from working properly. By inhibiting PDE5, Kamagra australia is able to activate guanylate cyclase, allowing more blood to flow to the penis.